MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE
Methylthio acetaldoxime
CAS: 10533-67-2
Molecular Formula: C3H7NOS
MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE - Names and Identifiers
MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE - Physico-chemical Properties
| Molecular Formula | C3H7NOS |
| Molar Mass | 105.16 |
| Density | 1.09±0.1 g/cm3(Predicted) |
| Boling Point | 209.2±23.0 °C(Predicted) |
| Flash Point | 80.335°C |
| Vapor Presure | 0.082mmHg at 25°C |
| pKa | 10.66±0.14(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.494 |
| Physical and Chemical Properties | Methomyl oxime neat as a white or pale yellow solid, M.P. 94~97 degrees C [93~95 degrees C (Z type),47~50 degrees C (E type)],74 degrees C within 24h does not decompose; 105 degrees C when 48h decomposition 93%. Methomyl oxime aqueous solution, pH = 7 12H does not decompose; pH = 2 24H decomposition 12%,72h decomposition 18% (both 25 degrees C), difficult to dissolve in water, soluble in organic solvents. |
| Use | Is an intermediate in the synthesis of methomyl |
MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE - Upstream Downstream Industry
| Raw Materials | Hydroxylamine hydrochloride acetaldehyde oxime Methanethiol,sodium salt |
| Downstream Products | Methomyl |
MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Uses | 1-methylthioacetaldehyde oxime is abbreviated as methomyl oxime. It is an intermediate with considerable economic value and can be used to make carbamate Insecticides such as methomyl, methomyl and cotton lingwei. is an intermediate for the synthesis of methomyl drugs |
| Production method | The key to the synthesis of methomyl is the synthesis of the intermediate methomyl oxime. The synthetic routes selected were different, and the yield of methomyl oxime was significantly separated from the cost. There are generally the following five methods for the synthesis of methomyl oxime: ① thioacetaldehyde oxime method; ② acetonitrile method; ③ methyl ethyl ketone method; ④ nitroethane method; ⑤ acetaldehyde method. In China, methomyl oxime is mainly produced by acetaldehyde method. The operation step of the acetaldehyde method is to react acetaldehyde and hydroxylamine hydrochloride under the action of an acid binding agent, and the generated acetaldoxime reacts with chlorine at a certain temperature. After a certain period of time, sodium methylmercaptan is added dropwise, and the pH is adjusted with alkali., Cooling, suction filtration, drying, the white crystal obtained is methomyl oxime. The reaction equation is as follows: CH3CHO NH2OH HCl NaOH → CH3CH = NOH NaCl 10 H2OCH3CH = NOH Cl2 → CH3CCl = NOH HClCH3CCl = NOH NaSCH3 → CH3-(SCH3)C = NOH NaCl The raw materials required for the acetaldehyde method are all made in China, with high product yield, low cost, no special requirements for equipment, and few "three wastes". It is currently the main method for producing methomyl oxime in the world. Both DuPont and Hunan Chemical Research Institute of the United States use the acetaldehyde method to produce methomyl oxime. |
Last Update：2024-04-09 20:52:54
Supplier List
View History
Raw Materials for MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE
Downstream Products for MethoMyl oxiMe,MHTA,METHYL-THIOACETOHYDROXAMATE